Abdi's Masnavi: Niyaz-name-i Sa'd u Huma

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A technique is described for the simultaneous and controlled random mutation of all three heavy or light chain complementaritj-determining regions (CDRs) in a single-chain Fv specific for the 0 polysaccharide of SalmoneUla serogroup B. Sense oligonucleotides were synthesized such that the central bases encoding a CDR were randomized by equimolar spiking with A, G, C, and T at a level of 10%/1 w...

Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing

A key challenge in the SAD phasing method is solving a structure when the anomalous signal-to-noise ratio is low. A simple theoretical framework for describing measurements of anomalous differences and the resulting useful anomalous correlation and anomalous signal in a SAD experiment is presented. Here, the useful anomalous correlation is defined as the correlation of anomalous differences wit...

I, G T   U

1 In the Beginning the Numbers Over the number of years, Conway [1, 2] has presented a fruitful theory to link numbers (number theory) and combinatorial games. This theory is useful in analyzing and to some extent predicting the outcome of games. Combinatorial games require the basic assumption that all moves are visible to both of the players and chance (dice) does not play any role. Thus, a g...

for u kit i

KNACK is a knowledge acquisition tool that generates expert systems for evaluating designs of electromechanical systems. An important feature of KNACK is that it acquires knowledge from domain experts without presupposing knowledge engineering skills on their part. This is achieved by incorporating general knowledge about evaluation tasks in KNACK. Using that knowledge, KNACK builds a conceptua...